Rybelsus (semaglutide) is an oral medication used to help manage blood sugar levels in adults with type 2 diabetes. It belongs to a class of medications known as GLP-1 receptor agonists, which work by mimicking the action of the glucagon-like peptide-1 (GLP-1) hormone. This hormone helps control blood sugar levels by: Stimulating the release of insulin in response to meals.Suppressing the release of glucagon (a hormone that increases blood sugar levels).Slowing down gastric emptying, which helps increase feelings of fullness and reduces appetite.