Acretin C Gel, which combines Clindamycin Phosphate 1.2% and Tretinoin 0.025% (or sometimes a higher concentration, depending on the formulation), is a topical treatment commonly prescribed for acne.Clindamycin Phosphate: This is an antibiotic that helps to reduce the number of acne-causing bacteria on the skin, thereby helping to prevent and treat acne breakouts.Tretinoin: A form of Vitamin A, tretinoin helps to speed up skin cell turnover, which can prevent pores from becoming clogged, thus reducing acne. It also helps improve skin texture and tone by promoting the exfoliation of dead skin cells.